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Apoptotic effects of high-dose rapamycin occur in S-phase of the cell cycle
Mutations in genes encoding regulators of mTOR, the mammalian target of rapamycin, commonly provide survival signals in cancer cells. Rapamycin and analogs of rapamycin have been used with limited success in clinical trials to target mTOR-dependent survival signals in a variety of human cancers. Sup...
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| Publicado no: | Cell Cycle |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4614271/ https://ncbi.nlm.nih.gov/pubmed/25945415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1046653 |
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