Lithocholic bile acid accumulated in yeast mitochondria orchestrates a development of an anti-aging cellular pattern by causing age-related changes in cellular proteome

We have previously revealed that exogenously added lithocholic bile acid (LCA) extends the chronological lifespan of the yeast Saccharomyces cerevisiae, accumulates in mitochondria and alters mitochondrial membrane lipidome. Here, we use quantitative mass spectrometry to show that LCA alters the age...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Cycle
Egile Nagusiak: Beach, Adam, Richard, Vincent R, Bourque, Simon, Boukh-Viner, Tatiana, Kyryakov, Pavlo, Gomez-Perez, Alejandra, Arlia-Ciommo, Anthony, Feldman, Rachel, Leonov, Anna, Piano, Amanda, Svistkova, Veronika, Titorenko, Vladimir I
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2015
Gaiak:
Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614269/
https://ncbi.nlm.nih.gov/pubmed/25839782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1026493
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