Lithocholic bile acid accumulated in yeast mitochondria orchestrates a development of an anti-aging cellular pattern by causing age-related changes in cellular proteome

We have previously revealed that exogenously added lithocholic bile acid (LCA) extends the chronological lifespan of the yeast Saccharomyces cerevisiae, accumulates in mitochondria and alters mitochondrial membrane lipidome. Here, we use quantitative mass spectrometry to show that LCA alters the age...

詳細記述

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書誌詳細
出版年:Cell Cycle
主要な著者: Beach, Adam, Richard, Vincent R, Bourque, Simon, Boukh-Viner, Tatiana, Kyryakov, Pavlo, Gomez-Perez, Alejandra, Arlia-Ciommo, Anthony, Feldman, Rachel, Leonov, Anna, Piano, Amanda, Svistkova, Veronika, Titorenko, Vladimir I
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2015
主題:
Report
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614269/
https://ncbi.nlm.nih.gov/pubmed/25839782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1026493
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