HIV-1 Tat protein induces glial cell autophagy through enhancement of BAG3 protein levels

BAG3 protein has been described as an anti-apoptotic and pro-autophagic factor in several neoplastic and normal cells. We previously demonstrated that BAG3 expression is elevated upon HIV-1 infection of glial and T lymphocyte cells. Among HIV-1 proteins, Tat is highly involved in regulating host cel...

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Veröffentlicht in:Cell Cycle
Hauptverfasser: Bruno, Anna Paola, De Simone, Francesca Isabella, Iorio, Vittoria, De Marco, Margot, Khalili, Kamel, Sariyer, Ilker Kudret, Capunzo, Mario, Nori, Stefania Lucia, Rosati, Alessandra
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2014
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Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614156/
https://ncbi.nlm.nih.gov/pubmed/25483098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.952959
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