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Genome-wide analysis of in vivo TRF1 binding to chromatin restricts its location exclusively to telomeric repeats

Telomeres are nucleoprotein structures at the ends of eukaryotic chromosomes that protect them from degradation, end-to-end fusions, and fragility. In mammals, telomeres are composed of TTAGGG tandem repeats bound by a protein complex called shelterin, which has fundamental roles in the regulation o...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Garrobo, Ianire, Marión, Rosa M, Domínguez, Orlando, Pisano, David G, Blasco, Maria A
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613987/
https://ncbi.nlm.nih.gov/pubmed/25483083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.965044
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