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EphA4 Receptor Forward Signaling Inhibits Glucagon Secretion From α-Cells

The loss of inhibition of glucagon secretion exacerbates hyperglycemia in type 1 and 2 diabetes. However, the molecular mechanisms that regulate glucagon secretion in unaffected and diabetic states remain relatively unexplained. We present evidence supporting a new model of juxtacrine-mediated regul...

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Bibliographic Details
Published in:Diabetes
Main Authors: Hutchens, Troy, Piston, David W.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613968/
https://ncbi.nlm.nih.gov/pubmed/26251403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0488
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