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Potent and Selective Inhibition of Plasma Membrane Monoamine Transporter by HIV Protease Inhibitors

Plasma membrane monoamine transporter (PMAT) is a major uptake-2 monoamine transporter that shares extensive substrate and inhibitor overlap with organic cation transporters 1–3 (OCT1–3). Currently, there are no PMAT-specific inhibitors available that can be used in in vitro and in vivo studies to d...

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Detalhes bibliográficos
Publicado no:Drug Metab Dispos
Main Authors: Duan, Haichuan, Hu, Tao, Foti, Robert S., Pan, Yongmei, Swaan, Peter W., Wang, Joanne
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613949/
https://ncbi.nlm.nih.gov/pubmed/26285765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.064824
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