Molecular Analysis and Structure-Activity Relationship Modeling of the Substrate/Inhibitor Interaction Site of Plasma Membrane Monoamine Transporter

Plasma membrane monoamine transporter (PMAT) is a new polyspecific transporter that interacts with a wide range of structurally diverse organic cations. To map the physicochemical descriptors of cationic compounds that allow interaction with PMAT, we systematically analyzed the interactions between...

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Detalhes bibliográficos
Main Authors: Ho, Horace T. B., Pan, Yongmei, Cui, Zhiyi, Duan, Haichuan, Swaan, Peter W., Wang, Joanne
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Metabolism, Transport, and Pharmacogenomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199987/
https://ncbi.nlm.nih.gov/pubmed/21816955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.184036
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