Selectivity in the Use of G(i/o) Proteins Is Determined by the DRF Motif in CXCR6 and Is Cell-Type Specific

CXCR6, the receptor for CXCL16, is expressed on multiple cell types and can be a coreceptor for human immunodeficiency virus 1. Except for CXCR6, all human chemokine receptors contain the D(3.49)R(3.50)Y(3.51) sequence, and all but two contain A(3.53) at the cytoplasmic terminus of the third transme...

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Publicado en:Mol Pharmacol
Autores principales: Singh, Satya P., Foley, John F., Zhang, Hongwei H., Hurt, Darrell E., Richards, Jennifer L., Smith, Craig S., Liao, Fang, Farber, Joshua M.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2015
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613941/
https://ncbi.nlm.nih.gov/pubmed/26316539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.115.099960
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