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Characterization of G protein coupling mediated by the conserved D134(3.49) of DRY motif, M241(6.34), and F251(6.44) residues on human CXCR1

CXCR1, a receptor for interleukin-8 (IL-8), plays an important role in defending against pathogen invasion during neutrophil-mediated innate immune response. Human CXCR1 is a G protein-coupled receptor (GPCR) with its characteristic seven transmembrane domains (TMs). Functional and structural analys...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Han, Xinbing, Feng, Yan, Chen, Xinhua, Gerard, Craig, Boisvert, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372616/
https://ncbi.nlm.nih.gov/pubmed/25834784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2015.03.001
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