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The menu of features that define primary microRNAs and enable de novo design of microRNA genes

MicroRNAs (miRNAs) are small regulatory RNAs processed from stem-loop regions of primary transcripts (pri-miRNAs), with the choice of stem-loops for initial processing largely determining what becomes a miRNA. To identify sequence and structural features influencing this choice, we determined cleava...

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Detalles Bibliográficos
Publicado en:Mol Cell
Main Authors: Fang, Wenwen, Bartel, David P.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613790/
https://ncbi.nlm.nih.gov/pubmed/26412306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.08.015
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