The oncogene EVI1 enhances transcriptional and biological responses of human myeloid cells to all-trans retinoic acid

The product of the ecotropic virus integration site 1 (EVI1) gene, whose overexpression is associated with a poor prognosis in myeloid leukemias and some epithelial tumors, regulates gene transcription both through direct DNA binding and through modulation of the activity of other sequence specific...

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Détails bibliographiques
Publié dans:Cell Cycle
Auteurs principaux: Steinmetz, Birgit, Hackl, Hubert, Slabáková, Eva, Schwarzinger, Ilse, Smějová, Monika, Spittler, Andreas, Arbesu, Itziar, Shehata, Medhat, Souček, Karel, Wieser, Rotraud
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2014
Sujets:
Reports
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613657/
https://ncbi.nlm.nih.gov/pubmed/25486480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.946869
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