The oncogene EVI1 enhances transcriptional and biological responses of human myeloid cells to all-trans retinoic acid

The product of the ecotropic virus integration site 1 (EVI1) gene, whose overexpression is associated with a poor prognosis in myeloid leukemias and some epithelial tumors, regulates gene transcription both through direct DNA binding and through modulation of the activity of other sequence specific...

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Publicado en:Cell Cycle
Autores principales: Steinmetz, Birgit, Hackl, Hubert, Slabáková, Eva, Schwarzinger, Ilse, Smějová, Monika, Spittler, Andreas, Arbesu, Itziar, Shehata, Medhat, Souček, Karel, Wieser, Rotraud
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2014
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Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613657/
https://ncbi.nlm.nih.gov/pubmed/25486480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.946869
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