Loss of CDK5RAP2 affects neural but not non-neural mESC differentiation into cardiomyocytes

Biallelic mutations in the gene encoding centrosomal CDK5RAP2 lead to autosomal recessive primary microcephaly (MCPH), a disorder characterized by pronounced reduction in volume of otherwise architectonical normal brains and intellectual deficit. The current model for the microcephaly phenotype in M...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Kraemer, Nadine, Ravindran, Ethiraj, Zaqout, Sami, Neubert, Gerda, Schindler, Detlev, Ninnemann, Olaf, Gräf, Ralph, Seiler, Andrea EM, Kaindl, Angela M
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613649/
https://ncbi.nlm.nih.gov/pubmed/25942099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1044169
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