CDK5RAP2 Is Required to Maintain the Germ Cell Pool during Embryonic Development

Gene products linked to microcephaly have been studied foremost for their role in brain development, while their function in the development of other organs has been largely neglected. Here, we report the critical role of Cdk5rap2 in maintaining the germ cell pool during embryonic development. We hi...

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Bibliografische gegevens
Hoofdauteurs: Sami Zaqout, Paraskevi Bessa, Nadine Krämer, Gisela Stoltenburg-Didinger, Angela M. Kaindl
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2017-02-01
Reeks:Stem Cell Reports
Onderwerpen:
CDK5RAP2
MCPH
microcephaly
intellectual disability
germline
infertility
cell cycle
mitotic delay
apoptosis
Online toegang:http://www.sciencedirect.com/science/article/pii/S2213671117300176
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