Fluoxetine Administration Exacerbates Oral Tremor and Striatal Dopamine Depletion in a Rodent Pharmacological Model of Parkinsonism

The cardinal motor symptoms of Parkinson’s disease (PD) include resting tremor, akinesia, bradykinesia, and rigidity, and these motor abnormalities can be modeled in rodents by administration of the VMAT-2 (type-2 vesicular monoamine transporter) inhibitor tetrabenazine (9,10-dimethoxy-3-(2-methylpr...

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Enregistré dans:
Détails bibliographiques
Publié dans:Neuropsychopharmacology
Auteurs principaux: Podurgiel, Samantha J, Milligan, Meredith N, Yohn, Samantha E, Purcell, Laura J, Contreras-Mora, Hector M, Correa, Mercè, Salamone, John D
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613615/
https://ncbi.nlm.nih.gov/pubmed/25759301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.69
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