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Fluoxetine Administration Exacerbates Oral Tremor and Striatal Dopamine Depletion in a Rodent Pharmacological Model of Parkinsonism

The cardinal motor symptoms of Parkinson’s disease (PD) include resting tremor, akinesia, bradykinesia, and rigidity, and these motor abnormalities can be modeled in rodents by administration of the VMAT-2 (type-2 vesicular monoamine transporter) inhibitor tetrabenazine (9,10-dimethoxy-3-(2-methylpr...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Podurgiel, Samantha J, Milligan, Meredith N, Yohn, Samantha E, Purcell, Laura J, Contreras-Mora, Hector M, Correa, Mercè, Salamone, John D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613615/
https://ncbi.nlm.nih.gov/pubmed/25759301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.69
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