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Effects of Fatty Acid Amide Hydrolase (FAAH) Inhibitors in Non-Human Primate Models of Nicotine Reward and Relapse

Inhibition of the enzyme fatty acid amide hydrolase (FAAH) counteracts reward-related effects of nicotine in rats, but it has not been tested for this purpose in non-human primates. Therefore, we studied the effects of the first- and second-generation O-arylcarbamate-based FAAH inhibitors, URB597 (c...

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Vydáno v:Neuropsychopharmacology
Hlavní autoři: Justinova, Zuzana, Panlilio, Leigh V, Moreno-Sanz, Guillermo, Redhi, Godfrey H, Auber, Alessia, Secci, Maria E, Mascia, Paola, Bandiera, Tiziano, Armirotti, Andrea, Bertorelli, Rosalia, Chefer, Svetlana I, Barnes, Chanel, Yasar, Sevil, Piomelli, Daniele, Goldberg, Steven R
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613608/
https://ncbi.nlm.nih.gov/pubmed/25754762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.62
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