A Double-Blind, Placebo-Controlled Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of JDTic

Animal studies suggest that kappa opioid receptor antagonists (KORAn) potentially could treat a wide variety of addictive and depressive disorders. We assessed the KORAn JDTic for safety, tolerability, and pharmacokinetics in a double-blind, placebo-controlled, randomized trial evaluating single ora...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Buda, Jeffrey J, Carroll, F I, Kosten, Thomas R, Swearingen, Dennis, Walters, Bradford B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613600/
https://ncbi.nlm.nih.gov/pubmed/25628006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.27
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