A randomized, double-blind, placebo controlled safety, tolerability, and pharmacokinetic dose escalation study of a gentamicin vancomycin gel in patients undergoing colorectal surgery

BACKGROUND: Despite numerous interventions promulgated by the Surgical Care Improve Project (SCIP) and other organizations, surgical site infection (SSI) continues to be a significant medical problem. DFA-02 is a novel bioresorbable modified-release gel consisting of both gentamicin (16.8 mg/mL) and...

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Detalhes bibliográficos
Publicado no:Perioper Med (Lond)
Main Authors: Bennett-Guerrero, Elliott, Minkowitz, Harold S., Segura-Vasi, Alvaro M., Marcet, Jorge E., White, Jennifer A., Corey, G Ralph, Allenby, Kent S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910209/
https://ncbi.nlm.nih.gov/pubmed/27313846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13741-016-0043-2
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