The NHERF2 sequence adjacent and upstream of the ERM-binding domain affects NHERF2–ezrin binding and dexamethasone stimulated NHE3 activity

In the brush border of intestinal and kidney epithelial cells, scaffolding proteins ezrin, Na(+)-H(+) exchanger regulatory factor (NHERF)1 and NHERF2 play important roles in linking transmembrane proteins to the cytoskeleton and assembling signalling regulatory complexes. The last 30 carboxyl residu...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Yang, Jianbo, Sarker, Rafiquel, Singh, Varsha, Sarker, Prateeti, Yin, Jianyi, Chen, Tian-E, Chaerkady, Raghothama, Li, Xuhang, Tse, C. Ming, Donowitz, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613507/
https://ncbi.nlm.nih.gov/pubmed/26251448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20150238
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