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High variability of genomic instability and gene expression profiling in different HeLa clones

The HeLa cell line is one of the most popular cell lines in biomedical research, despite its well-known chromosomal instability. We compared the genomic and transcriptomic profiles of 4 different HeLa batches and showed that the gain and loss of genomic material varies widely between batches, drasti...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Frattini, Annalisa, Fabbri, Marco, Valli, Roberto, De Paoli, Elena, Montalbano, Giuseppe, Gribaldo, Laura, Pasquali, Francesco, Maserati, Emanuela
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613361/
https://ncbi.nlm.nih.gov/pubmed/26483214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15377
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