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Cisplatin Targeting of Bacterial Ribosomal RNA Hairpins

Cisplatin is a clinically important chemotherapeutic agent known to target purine bases in nucleic acids. In addition to major deoxyribonucleic acid (DNA) intrastrand cross-links, cisplatin also forms stable adducts with many types of ribonucleic acid (RNA) including siRNA, spliceosomal RNAs, tRNA,...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Dedduwa-Mudalige, Gayani N. P., Chow, Christine S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613259/
https://ncbi.nlm.nih.gov/pubmed/26370969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160921392
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