Weekly Treatment of 2-Hydroxypropyl-β-cyclodextrin Improves Intracellular Cholesterol Levels in LDL Receptor Knockout Mice

Recently, the importance of lysosomes in the context of the metabolic syndrome has received increased attention. Increased lysosomal cholesterol storage and cholesterol crystallization inside macrophages have been linked to several metabolic diseases, such as atherosclerosis and non-alcoholic fatty...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Walenbergh, Sofie M. A., Houben, Tom, Hendrikx, Tim, Jeurissen, Mike L. J., van Gorp, Patrick J., Vaes, Nathalie, Olde Damink, Steven W. M., Verheyen, Fons, Koek, Ger H., Lütjohann, Dieter, Grebe, Alena, Latz, Eicke, Shiri-Sverdlov, Ronit
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613241/
https://ncbi.nlm.nih.gov/pubmed/26404254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160921056
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