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Fasting protects against the side effects of irinotecan but preserves its anti-tumor effect in Apc15lox mutant mice
Irinotecan is a widely used topoisomerase-I-inhibitor with a very narrow therapeutic window because of its severe toxicity. In the current study we have examined the effects of fasting prior to irinotecan treatment on toxicity and anti-tumor activity. FabplCre;Apc(15lox/+) mice, which spontaneously...
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| Pubblicato in: | Cell Cycle |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4613178/ https://ncbi.nlm.nih.gov/pubmed/25955194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1044170 |
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