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MDM2 binds and inhibits vitamin D receptor

The E3 ubiquitin ligase and transcriptional repressor MDM2 is a potent inhibitor of the p53 family of transcription factors and tumor suppressors. Herein, we report that vitamin D receptor (VDR), another transcriptional regulator and probably, tumor suppressor, is also bound and inhibited by MDM2. T...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Heyne, Kristina, Heil, Tessa-Carina, Bette, Birgit, Reichrath, Jörg, Roemer, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613177/
https://ncbi.nlm.nih.gov/pubmed/25969952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1044176
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