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Allopregnanolone attenuates Aβ(25-35)-induced neurotoxicity in PC12 cells by reducing oxidative stress
Massive accumulation of amyloid beta (Aβ) has been implicated as a pivotal event in the pathogenesis of Alzheimer’s disease. The underlying mechanisms of Aβ-induced neurotoxicity include generation of reactive oxidative species (ROS), inflammation, and neurons loss. Allopregnano-lone (APα), a neuros...
Tallennettuna:
| Julkaisussa: | Int J Clin Exp Med |
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| Päätekijät: | , , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
e-Century Publishing Corporation
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4612987/ https://ncbi.nlm.nih.gov/pubmed/26550302 |
| Tagit: |
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