Allopregnanolone attenuates Aβ(25-35)-induced neurotoxicity in PC12 cells by reducing oxidative stress

Massive accumulation of amyloid beta (Aβ) has been implicated as a pivotal event in the pathogenesis of Alzheimer’s disease. The underlying mechanisms of Aβ-induced neurotoxicity include generation of reactive oxidative species (ROS), inflammation, and neurons loss. Allopregnano-lone (APα), a neuros...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Clin Exp Med
Prif Awduron: Qian, Xiaowei, Cao, Hong, Ma, Qian, Wang, Qinsai, He, Wei, Qin, Peishun, Ji, Bin, Yuan, Kaiming, Yang, Fanghua, Liu, Xuhua, Lian, Qingquan, Li, Jun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: e-Century Publishing Corporation 2015
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612987/
https://ncbi.nlm.nih.gov/pubmed/26550302
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg