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Sphingosine kinase 1/sphingosine 1-phosphate signalling pathway as a potential therapeutic target of pulmonary hypertension
Pulmonary hypertension is characterized by extensive vascular remodelling, leading to increased pulmonary vascular resistance and eventual death due to right heart failure. The pathogenesis of pulmonary hypertension involves vascular endothelial dysfunction and disordered vascular smooth muscle cell...
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發表在: | Int J Clin Exp Med |
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Main Authors: | , , , , , , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
e-Century Publishing Corporation
2015
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4612791/ https://ncbi.nlm.nih.gov/pubmed/26550106 |
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