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Sphingosine kinase 1/sphingosine 1-phosphate signalling pathway as a potential therapeutic target of pulmonary hypertension

Pulmonary hypertension is characterized by extensive vascular remodelling, leading to increased pulmonary vascular resistance and eventual death due to right heart failure. The pathogenesis of pulmonary hypertension involves vascular endothelial dysfunction and disordered vascular smooth muscle cell...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Med
Main Authors: Xing, Xi-Qian, Li, Yan-Li, Zhang, Yu-Xuan, Xiao, Yi, Li, Zhi-Dong, Liu, Li-Qiong, Zhou, Yu-Shan, Zhang, Hong-Yan, Liu, Yan-Hong, Zhang, Li-Hui, Zhuang, Min, Chen, Yan-Ping, Ouyang, Sheng-Rong, Wu, Xu-Wei, Yang, Jiao
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612791/
https://ncbi.nlm.nih.gov/pubmed/26550106
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