Sphingosine kinase 1/sphingosine 1-phosphate signalling pathway as a potential therapeutic target of pulmonary hypertension

Pulmonary hypertension is characterized by extensive vascular remodelling, leading to increased pulmonary vascular resistance and eventual death due to right heart failure. The pathogenesis of pulmonary hypertension involves vascular endothelial dysfunction and disordered vascular smooth muscle cell...

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Bibliographic Details
Published in:Int J Clin Exp Med
Main Authors: Xing, Xi-Qian, Li, Yan-Li, Zhang, Yu-Xuan, Xiao, Yi, Li, Zhi-Dong, Liu, Li-Qiong, Zhou, Yu-Shan, Zhang, Hong-Yan, Liu, Yan-Hong, Zhang, Li-Hui, Zhuang, Min, Chen, Yan-Ping, Ouyang, Sheng-Rong, Wu, Xu-Wei, Yang, Jiao
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2015
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Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612791/
https://ncbi.nlm.nih.gov/pubmed/26550106
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