Sphingosine kinase 1/sphingosine 1-phosphate signalling pathway as a potential therapeutic target of pulmonary hypertension

Pulmonary hypertension is characterized by extensive vascular remodelling, leading to increased pulmonary vascular resistance and eventual death due to right heart failure. The pathogenesis of pulmonary hypertension involves vascular endothelial dysfunction and disordered vascular smooth muscle cell...

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Vydáno v:Int J Clin Exp Med
Hlavní autoři: Xing, Xi-Qian, Li, Yan-Li, Zhang, Yu-Xuan, Xiao, Yi, Li, Zhi-Dong, Liu, Li-Qiong, Zhou, Yu-Shan, Zhang, Hong-Yan, Liu, Yan-Hong, Zhang, Li-Hui, Zhuang, Min, Chen, Yan-Ping, Ouyang, Sheng-Rong, Wu, Xu-Wei, Yang, Jiao
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2015
Témata:
Review Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612791/
https://ncbi.nlm.nih.gov/pubmed/26550106
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