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Inhibition of protein phosphatase 2A with the small molecule LB100 overcomes cell cycle arrest in osteosarcoma after cisplatin treatment

Osteosarcoma is the most common primary malignant bone tumor and affects a significant portion of pediatric oncology patients. Although surgery and adjuvant chemotherapy confer significant survival benefits, many patients go on to develop metastatic disease, particularly to the lungs, secondary to d...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Zhang, Chao, Hong, Christopher S, Hu, Xu, Yang, Chunzhang, Wang, Herui, Zhu, Dongwang, Moon, Seogin, Dmitriev, Pauline, Lu, Jie, Chiang, Jeffrey, Zhuang, Zhengping, Zhou, Yue
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612123/
https://ncbi.nlm.nih.gov/pubmed/25942376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1041693
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