The role of Cullin3-mediated ubiquitination of the catalytic subunit of PP2A in TRAIL signaling

Protein phosphatase 2A (PP2A) is the major serine-threonine phosphatase that regulates a number of cell signaling pathways. PP2A activity is controlled partially through protein degradation; however, the underlying mechanism is not fully understood. Here we show that PP2A/C, a catalytic subunit of P...

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Published in:Cell Cycle
Main Authors: Xu, Jing, Zhou, Jun-Ying, Xu, Zhengfan, Kho, Dhong-Hyo, Zhuang, Zhengping, Raz, Avraham, Wu, Gen Sheng
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612120/
https://ncbi.nlm.nih.gov/pubmed/25551360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.965068
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