Interleukin-27 inhibits ectopic lymphoid-like structure development in early inflammatory arthritis

Ectopic lymphoid-like structures (ELSs) reminiscent of secondary lymphoid organs often develop at sites of chronic inflammation where they contribute to immune-mediated pathology. Through evaluation of synovial tissues from rheumatoid arthritis (RA) patients, we now show that low interleukin-27 (IL-...

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Détails bibliographiques
Publié dans:J Exp Med
Auteurs principaux: Jones, Gareth W., Bombardieri, Michele, Greenhill, Claire J., McLeod, Louise, Nerviani, Alessandra, Rocher-Ros, Vidalba, Cardus, Anna, Williams, Anwen S., Pitzalis, Costantino, Jenkins, Brendan J., Jones, Simon A.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2015
Sujets:
Brief Definitive Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612100/
https://ncbi.nlm.nih.gov/pubmed/26417004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20132307
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