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Ectopic Lymphoid Structures Support Ongoing Production of Class-Switched Autoantibodies in Rheumatoid Synovium

BACKGROUND: Follicular structures resembling germinal centres (GCs) that are characterized by follicular dendritic cell (FDC) networks have long been recognized in chronically inflamed tissues in autoimmune diseases, including the synovium of rheumatoid arthritis (RA). However, it is debated whether...

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Hlavní autoři: Humby, Frances, Bombardieri, Michele, Manzo, Antonio, Kelly, Stephen, Blades, Mark C, Kirkham, Bruce, Spencer, Jo, Pitzalis, Costantino
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2621263/
https://ncbi.nlm.nih.gov/pubmed/19143467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0060001
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