Ectopic Lymphoid Structures Support Ongoing Production of Class-Switched Autoantibodies in Rheumatoid Synovium

BACKGROUND: Follicular structures resembling germinal centres (GCs) that are characterized by follicular dendritic cell (FDC) networks have long been recognized in chronically inflamed tissues in autoimmune diseases, including the synovium of rheumatoid arthritis (RA). However, it is debated whether...

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Main Authors: Humby, Frances, Bombardieri, Michele, Manzo, Antonio, Kelly, Stephen, Blades, Mark C, Kirkham, Bruce, Spencer, Jo, Pitzalis, Costantino
格式: Artigo
語言:Inglês
出版: Public Library of Science 2009
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2621263/
https://ncbi.nlm.nih.gov/pubmed/19143467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0060001
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