The effect of adenovirus expressing wild-type p53 on 5-fluorouracil chemosensitivity is related to p53 status in pancreatic cancer cell lines

AIM: There are conflicting data about p53 function on cellular sensitivity to the cytotoxic action of 5-fluorouracil (5-FU). Therefore the objective of this study was to determine the combined effects of adenovirus-mediated wild-type (wt) p53 gene transfer and 5-FU chemotherapy on pancreatic cancer...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:World J Gastroenterol
Prif Awduron: Eisold, Sven, Linnebacher, Michael, Ryschich, Eduard, Antolovic, Dalibor, Hinz, Ulf, Klar, Ernst, Schmidt, Jan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Baishideng Publishing Group Inc 2004
Pynciau:
Basic Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611997/
https://ncbi.nlm.nih.gov/pubmed/15534911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i24.3583
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