IGFBP7 induces apoptosis of acute myeloid leukemia cells and synergizes with chemotherapy in suppression of leukemia cell survival

Despite high remission rates after chemotherapy, only 30–40% of acute myeloid leukemia (AML) patients survive 5 years after diagnosis. This extremely poor prognosis of AML is mainly caused by treatment failure due to chemotherapy resistance. Chemotherapy resistance can be caused by various features...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Verhagen, H JMP, de Leeuw, D C, Roemer, M GM, Denkers, F, Pouwels, W, Rutten, A, Celie, P H, Ossenkoppele, G J, Schuurhuis, G J, Smit, L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611740/
https://ncbi.nlm.nih.gov/pubmed/24967962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.268
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