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Bcl-xL controls a switch between cell death modes during mitotic arrest

Antimitotic agents such as microtubule inhibitors (paclitaxel) are widely used in cancer therapy while new agents blocking mitosis onset are currently in development. All these agents impose a prolonged mitotic arrest in cancer cells that relies on sustained activation of the spindle assembly checkp...

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Podrobná bibliografie
Vydáno v:Cell Death Dis
Hlavní autoři: Bah, N, Maillet, L, Ryan, J, Dubreil, S, Gautier, F, Letai, A, Juin, P, Barillé-Nion, S
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611724/
https://ncbi.nlm.nih.gov/pubmed/24922075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.251
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