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Metabotropic glutamate receptor signaling is required for NMDA receptor-dependent ocular dominance plasticity and LTD in visual cortex

A feature of early postnatal neocortical development is a transient peak in signaling via metabotropic glutamate receptor 5 (mGluR5). In visual cortex, this change coincides with increased sensitivity of excitatory synapses to monocular deprivation (MD). However, loss of visual responsiveness after...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sidorov, Michael S., Kaplan, Eitan S., Osterweil, Emily K., Lindemann, Lothar, Bear, Mark F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611661/
https://ncbi.nlm.nih.gov/pubmed/26417096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1512878112
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