STIM1–Ca(2+) signaling modulates automaticity of the mouse sinoatrial node

Cardiac pacemaking is governed by specialized cardiomyocytes located in the sinoatrial node (SAN). SAN cells (SANCs) integrate voltage-gated currents from channels on the membrane surface (membrane clock) with rhythmic Ca(2+) release from internal Ca(2+) stores (Ca(2+) clock) to adjust heart rate to...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhang, Hengtao, Sun, Albert Y., Kim, Jong J., Graham, Victoria, Finch, Elizabeth A., Nepliouev, Igor, Zhao, Guiling, Li, Tianyu, Lederer, W. J., Stiber, Jonathan A., Pitt, Geoffrey S., Bursac, Nenad, Rosenberg, Paul B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611639/
https://ncbi.nlm.nih.gov/pubmed/26424448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503847112
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