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NhaA antiporter functions using 10 helices, and an additional 2 contribute to assembly/stability

The Escherichia coli Na(+)/H(+) antiporter (Ec-NhaA) is the best-characterized of all pH-regulated Na(+)/H(+) exchangers that control cellular Na(+) and H(+) homeostasis. Ec-NhaA has 12 helices, 2 of which (VI and VII) are absent from other antiporters that share the Ec-NhaA structural fold. This α-...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Padan, Etana, Danieli, Tsafi, Keren, Yael, Alkoby, Dudu, Masrati, Gal, Haliloglu, Turkan, Ben-Tal, Nir, Rimon, Abraham
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611637/
https://ncbi.nlm.nih.gov/pubmed/26417087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510964112
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