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Pleckstrin homology domain of G protein-coupled receptor kinase-2 binds to PKC and affects the activity of PKC kinase
AIM: To study the detail mechanism of interaction between PKC and GRK(2) and the effect of GRK(2) on activity of PKC. METHODS: The cDNA of pleckstrin homology (PH) domain located in GRK(2) residue 548 to 660 was amplified by PCR with the mRNA of human GRK(2) (β1-adrenergic receptor kinase) as templa...
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| Publié dans: | World J Gastroenterol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Baishideng Publishing Group Inc
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4611453/ https://ncbi.nlm.nih.gov/pubmed/12679936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v9.i4.800 |
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