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Pleckstrin homology domain of G protein-coupled receptor kinase-2 binds to PKC and affects the activity of PKC kinase

AIM: To study the detail mechanism of interaction between PKC and GRK(2) and the effect of GRK(2) on activity of PKC. METHODS: The cDNA of pleckstrin homology (PH) domain located in GRK(2) residue 548 to 660 was amplified by PCR with the mRNA of human GRK(2) (β1-adrenergic receptor kinase) as templa...

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Bibliografische gegevens
Gepubliceerd in:World J Gastroenterol
Hoofdauteurs: Yang, Xing-Long, Zhang, Ya-Li, Lai, Zhuo-Sheng, Xing, Fei-Yue, Liu, Yu-Hu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Baishideng Publishing Group Inc 2003
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611453/
https://ncbi.nlm.nih.gov/pubmed/12679936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v9.i4.800
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