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Mutation and methylation of hMLH1 in gastric carcinomas with microsatellite instability

AIM: To appraise the correlation of mutation and methylation of hMSH1 with microsatellite instability (MSI) in gastric cancers. METHODS: Mutation of hMLH1 was detected by Two-dimensional electrophoresis (Two-D) and DNA sequencing; Methylation of hMLH1 promoter was measured with methylation-specific...

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Publicado en:World J Gastroenterol
Main Authors: Fang, Dian-Chun, Wang, Rong-Quan, Yang, Shi-Ming, Yang, Jian-Ming, Liu, Hai-Feng, Peng, Gui-Yong, Xiao, Tian-Li, Luo, Yuan-Hui
Formato: Artigo
Idioma:Inglês
Publicado: Baishideng Publishing Group Inc 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611422/
https://ncbi.nlm.nih.gov/pubmed/12679904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v9.i4.655
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