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Exploring Internal Ribosome Entry Sites as Therapeutic Targets

Initiation of eukaryotic mRNA translation may proceed via several different routes, each requiring a different subset of factors and relying on different and specific interactions between the mRNA and the ribosome. Two modes predominate: (i) so-called cap-dependent initiation, which requires all can...

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Bibliografische gegevens
Gepubliceerd in:Front Oncol
Hoofdauteurs: Komar, Anton A., Hatzoglou, Maria
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611151/
https://ncbi.nlm.nih.gov/pubmed/26539410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00233
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