DNA Copy Number Changes at 8q11–24 in Metastasized Colorectal Cancer

Background: C-Myc, a well-known oncogene located on 8q24.12–q24.23, is often amplified and over-expressed in both primary and metastasizing colorectal cancer. In addition, PRL-3 (also known as PTP4A3), a tyrosine phosphatase located on 8q24.3, is amplified in colorectal cancer metastasis. Beside PRL...

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Pubblicato in:Cell Oncol
Autori principali: Buffart, T. E., Coffa, J., Hermsen, M. A. J. A., Carvalho, B., van der Sijp, J. R. M., Ylstra, B., Pals, G., Schouten, J. P., Meijer, G. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: IOS Press 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611113/
https://ncbi.nlm.nih.gov/pubmed/15750208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2005/401607
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