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Inducing Oncoprotein Degradation to Improve Targeted Cancer Therapy()

Over the past decade, inhibition of the kinase activities of oncogenic proteins using small molecules and antibodies has been a mainstay of our anticancer drug development effort, resulting in several Food and Drug Administration–approved cancer therapies. The clinical effectiveness of kinase-target...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Ray, Dipankar, Cuneo, Kyle C., Rehemtulla, Alnawaz, Lawrence, Theodore S., Nyati, Mukesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611070/
https://ncbi.nlm.nih.gov/pubmed/26476077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2015.08.008
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