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Quantitative time-resolved analysis reveals intricate, differential regulation of standard- and immuno-proteasomes
Proteasomal protein degradation is a key determinant of protein half-life and hence of cellular processes ranging from basic metabolism to a host of immunological processes. Despite its importance the mechanisms regulating proteasome activity are only incompletely understood. Here we use an iterativ...
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| Publié dans: | eLife |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4611054/ https://ncbi.nlm.nih.gov/pubmed/26393687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07545 |
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