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Differential requirements of TCR signaling in homeostatic maintenance and function of Dendritic Epidermal T Cells

Dendritic Epidermal T Cells (DETCs) are generated exclusively in the fetal thymus and maintained in the skin epithelium throughout postnatal life of the mouse. DETCs have restricted antigenic specificity due to their exclusive usage of a canonical TCR. Although the importance of the TCR in DETC deve...

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Vydáno v:J Immunol
Hlavní autoři: Zhang, Baojun, Wu, Jianxuan, Jiao, Yiqun, Bock, Cheryl, Dai, Meifang, Chen, Benny, Chao, Nelson, Zhang, Weiguo, Zhuang, Yuan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610875/
https://ncbi.nlm.nih.gov/pubmed/26408667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501220
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