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Persistent SIV infection causes ultimate depletion of follicular T helper cells in AIDS

Follicular CD4+ T helper (Tfh) cells are critical for the generation of humoral immune responses to pathogenic infections, providing help for B cell development, survival, and affinity maturation of antibodies. Although CD4+ Tfh cells are reported to accumulate in HIV or SIV infection, here we found...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Xu, Huanbin, Wang, Xiaolei, Malam, Naomi, Lackner, Andrew A, Veazey, Ronald S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610871/
https://ncbi.nlm.nih.gov/pubmed/26408660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501273
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