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Persistent SIV infection causes ultimate depletion of follicular T helper cells in AIDS
Follicular CD4+ T helper (Tfh) cells are critical for the generation of humoral immune responses to pathogenic infections, providing help for B cell development, survival, and affinity maturation of antibodies. Although CD4+ Tfh cells are reported to accumulate in HIV or SIV infection, here we found...
Enregistré dans:
Publié dans: | J Immunol |
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Auteurs principaux: | , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
2015
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4610871/ https://ncbi.nlm.nih.gov/pubmed/26408660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501273 |
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